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2-Bromoethanol 2-溴乙醇

规格: 98%
CAS: 540-51-2
产品编号: H20612
MDL: MFCD00002827
品牌: INFI
Chemical Name2-Bromoethanol
CAS Number540-51-2
EC Number208-748-1
Reaxys-RN878140
Merck Number3792
Beilstein Registry Number878140
PubChem Substance ID10898
MDL NumberMFCD00002827
Synonym -Bromoethylalcohol 1-Bromo-2-ethanol 1-Bromo-2-hydroxyethane 2-BROMOETHANOL, 1000MG, NEAT 2-Bromethanol 2-Bromo Ethenol 2-Bromoethanol 2-Bromoethyl alcohol 2-bromo-1-ethanol 2-bromoetanol 2-hydroxyethylbromide 2-溴乙醇 Bromoethanol CH2BrCH2OH(trans) ETHYLENE BROMOHYDRIN Ethanol, 2-bromo- Ethylenbromhydrin Ethylene bromohydrin Ethylene bromohydrin2-Hydroxyethyl bromide ethylene bromohydrine glycolbromohydrin Β-溴乙醇 亚乙基溴醇 亚乙基溴醇; 溴乙醇; 2-溴代乙醇 溴乙醇
Chemical Name Translation2-溴乙醇
Wiswesser Line NotationQ2E
LabNetwork Molecule IDLN00195719
InChIInChI=1S/C2H5BrO/c3-1-2-4/h4H,1-2H2
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg/8W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   39,391,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 43 gm/kg/80W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 2(2),246,1983

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   23,288,1972

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Klebsiella pneumoniae
DOSE/DURATION           : 15 mmol/L
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 25,85,1969

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   11(Suppl 12),1,1988

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 10 umol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 26,367,1974

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 20 uL/disc
REFERENCE :
   AEMIDF Applied and Environmental Microbiology.  (American Soc. for
   Microbiology, 1913 I St., NW, Washington, DC 20006)  V.31-    1976-
   Volume(issue)/page/year: 43,177,1982

WGK Germany3
Hazard statements
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H301+H311+H331
  • H227 Combustible liquid 可燃液体
    Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    Hazard Codes 8 T T,T+
    RTECSKJ8225000
    Precautionary statements
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
    • P301+P310
    • P301+P330+P331+P310
    • P304+P340+P310
    • P305+P351+P338
    • P305+P351+P338+P310
    • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
    • P403+P233
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      UN Number 2922
      Storage condition Light Sensitive & Hygroscopic <;0 储存温度2-8℃ Light Sensitive <0°C 2-8°C 避光保存
      Risk Statements
      • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
      • R34 Causes burns 会导致灼伤
        Safety Statements
        • S20 When using do not eat or drink 使用时，不得进食，饮水；
        • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
        • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
        • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服；
        • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
        • S4 Keep away from living quarters 远离生活区；
        • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
        • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
        • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；
          Packing GroupII
          Hazard Class8/6.1
          Warnings 危化品目录(2015)
          Restrict 危险品
        • 可用于硝基芳烃（PcFe(II)/NaBH4/2-溴乙醇催化体系）的选择还原反应。
        • {ALF} Carboxylic acids protected as their 2-bromoethyl esters are readily deprotected by cleavage with sodium trithiocarbonate: Synthesis, 715 (1974). 2-Bromoethyl esters of amino acids have been cleaved by conversion with NaI (Finkelstein) to the corresponding iodo esters, followed by reductive cleavage with Zn in DMF: Chem. Ber., 112, 2145 (1979); Angew. Chem. Int. Ed., 20, 894 (1981). See also Appendix 6.
        • {uni_hamburg} Short: II/6
        • {ALD} Merck:14,3792
        • {uni_hamburg} Short: II/25B
        • {ALD} Merck:14,3792
        • Beilstein:1,338
          • 540-51-2 H20612 2-Bromoethanol 2-溴乙醇

          化学属性

          Mol. FormulaBrCH2CH2OH
          Mol. Weight125
          Refractive index1.4880 to 1.4920
          Density1.743
          Flash Point>230 °F
          TSCAYes
          Boiling Point56 - 57 °C 20 mm Hg(lit.)
          Melting Point-83 - -77 °C
          Vapor Density4.3 (vs air)
          Vapor Pressure2.4 mmHg ( 20 °C)
          SolubilitySoluble in water
          Stability对热、湿度及光敏感
          pH:A

          *以上化合物性质及应用等信息仅供参考

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